Septerna, Inc. (SEPN): insider trading, Congress trades & who owns it

Insider signal
20/100
Heavy insider selling · 90 days
Insider buys
$0
0 buyers · 12 months
Insider sales
$76.1M
5 sellers · 12 months
Funds holding
154
13F · Q2 2026
Congress trades
None
none in 2 years

Insider activity at Septerna, Inc. has been all selling for a year now: about $76.1 million from five sellers, and zero buyers on the open market.

Selling on its own is common and often pre-planned (10b5-1 plans, taxes, diversification), so it matters more when it is unusually heavy or broad.

Zooming out by quarter: 4 quarters in a row of net selling by insiders. Insiders bought in 1 of the last 7 full quarters. 154 investment managers listed SEPN in their latest 13F filings (Q2 2026); more funds bought than sold.

Want the full picture on SEPN? Financials, dilution history, a written bull & bear case, top holders and alerts.
See the full SEPN report — free account

Latest insider trades in SEPN

FiledInsiderRoleTypeSharesPriceValueSource
Sep 3, 2026Long Daniel D.Executive OfficerSell3,333$37.83$126KSEC
Aug 14, 2026Third Rock Ventures GP VI, L.P.10% OwnerSell141$51.08$7KSEC
Aug 14, 2026Third Rock Ventures GP VI, L.P.10% OwnerSell147,059$50.27$7.4MSEC
Aug 14, 2026Shah Rajeev M.DirectorSell746,500$42.50$31.7MSEC
Aug 14, 2026Shah Rajeev M.DirectorSell746,500$42.50$31.7MSEC
Aug 13, 2026Bhatt ElizabethCOOSell25,000$44.00$1.1MSEC
Aug 5, 2026Long Daniel D.Executive OfficerSell2,334$34.68$81KSEC
Aug 5, 2026Long Daniel D.Executive OfficerSell1,000$33.98$34KSEC
Jul 17, 2026Bhatt ElizabethCOOSell4,000$33.99$136KSEC
Jul 2, 2026Long Daniel D.Executive OfficerSell1,233$34.81$43KSEC
Jul 2, 2026Long Daniel D.Executive OfficerSell2,100$34.10$72KSEC
Jun 30, 2026Shaikhly SamiraExecutive OfficerSell2,178$35.18$77KSEC
Jun 24, 2026Long Daniel D.Executive OfficerSell7,000$35.97$252KSEC
Jun 24, 2026Long Daniel D.Executive OfficerSell8,000$35.10$281KSEC
Jun 16, 2026Shaikhly SamiraExecutive OfficerSell6,250$35.08$219KSEC

Questions about SEPN

Are insiders buying or selling SEPN stock?

In the last 12 months Septerna, Inc. insiders made open-market purchases worth about $0 and sales worth about $76.1 million. Data comes from SEC Form 4 filings, updated every 30 minutes on CapitalSnitch.

When was the last insider trade in SEPN?

The most recent open-market insider trade in SEPN was filed on 2026-09-03.

How many institutions own SEPN?

154 investment managers reported holding SEPN in SEC Form 13F filings for Q2 2026.

Has any member of Congress traded SEPN?

No congressional trades in SEPN were reported in the past two years. The full list is free on CapitalSnitch.

Also active in insider buying

Free weekly email: the week's biggest insider buys and Congress trades, every Monday. No spam, one-click unsubscribe.

Public-record data for research and education, not investment advice. Insider sales are often pre-planned (10b5-1). Congress data: Data derived from public disclosures filed under the Ethics in Government Act and the STOCK Act, republished free for public transparency and news reporting. Disclosures may lag the trade by 45 days or more and show amounts only as ranges. This data may not be used for credit rating, loan underwriting, solicitation of money (political, charitable or other), direct-mail or commercial targeting (5 U.S.C. 13107).